Developmental Patterning of Irritability Enhances Prediction of Psychopathology in Pre-adolescence: Improving RDoC with Developmental Science

Abstract excerpt

Research has demonstrated the transdiagnostic importance of irritability in psychopathology pathways but the contribution of developmentally-unfolding patterns has only recently been explored. To address this question, irritability patterns of 110 youth from a large and diverse early childhood cohort were assessed at preschool age and at school age (∼2.5 years later) with a dimensional irritability scale designed...

Topics

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• Adolescent
• Attention Deficit Disorder with Hyperactivity
• Child
• Depressive Disorder, Major
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Longitudinal Studies
• Multifactorial Inheritance

Identifiers and source

Literature Corpus work

6531d6a8-ad73-5ac6-a616-27b58e388ed6

DOI

10.1101/2020.04.30.070714