Article

Human umbilical mesenchymal stem cell-derived mitochondria ameliorate maternal phenotype by improving placental mitochondria and vascular function in angiotensin II-induced preeclampsia rat

2024-05-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mitochondrial transplantation (Mito-T) is a novel therapeutic strategy targeting ischemic cardiovascular diseases. Here, we tested the efficacy of human umbilical mesenchymal stem cell-derived mitochondria transplantation (Mito-T) on a rat model of PE. <h4>Methods</h4> PE was induced by infusing angiotensin II (Ang II) to SD pregnancy rats on gestation day 8 (GD 8). Mito-T...

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Literature Corpus work: 64d45d29-8835-5b88-ac7e-0ca1d0a2e70a
DOI: 10.1101/2024.05.08.592162

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