Article

Umbilical cord mesenchymal stem cells improve PINK1/PARKIN-mediated mitophagy inhibition in preeclampsia

2026-06-08

Abstract excerpt

<title>Abstract</title> <p>Background Preeclampsia (PE) is a progressive multisystem disorder that arises after 20 weeks of gestation and poses severe risks to both maternal and fetal health. Umbilical cord mesenchymal stem cells (UC-MSCs) exhibit antioxidant and pro-angiogenic properties, which have been shown to be effective in treating various diseases. Methods HTR8/SVneo cells were induced by lipopolysaccha...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ea06dc7-e285-5228-8754-e0152fb8c7c9
DOI: 10.21203/rs.3.rs-9714444/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Umbilical cord mesenchymal stem cells improve PINK1/PARKIN-mediated mitophagy inhibition in preeclampsiaDOI 10.21203/rs.3.rs-9714444/v1Read

Human umbilical cord mesenchymal stem cells restores mTOR-mediated autophagy homeostasis to alleviate placental injury and improve pregnancy outcomes in preeclampsiaSemantic proximity Read

Human umbilical mesenchymal stem cell-derived mitochondria ameliorate maternal phenotype by improving placental mitochondria and vascular function in angiotensin II-induced preeclampsia ratSemantic proximity Read

Current Studies of Mitochondrial Quality Control in the PreeclampsiaSemantic proximity Read

Mitochondrial Dysfunction, Mitophagy and Their Correlation with Perinatal Complications: Preeclampsia and Low Birth WeightSemantic proximity Read

Proteomics Analysis Reveals Abnormal Electron Transport and Excessive Oxidative Stress Cause Mitochondrial Dysfunction in Placental Tissues of Early‐Onset PreeclampsiaSemantic proximity Read

Placental Mitochondrial Abnormalities in PreeclampsiaSemantic proximity Read

Role of DRAM1 in mitophagy contributes to preeclampsia regulation in miceSemantic proximity Read

Dichotomy in hypoxia-induced mitochondrial fission in placental mesenchymal cells during development and preeclampsia: consequences for trophoblast mitochondrial homeostasisSemantic proximity Read

Exploring the Importance of Differential Expression of Autophagy Markers in Term Placentas from Late-Onset Preeclamptic PregnanciesSemantic proximity Read

Impact of ferroptosis on preeclampsia: A reviewSemantic proximity Read

The Role of Mitochondrial Dysfunction in Preeclampsia: Causative Factor or Collateral Damage?Semantic proximity Read

Mitochondrial quality control alterations and placenta-related disordersSemantic proximity Read