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Transcriptomic analysis reveals that severity of infectious bursal disease in White Leghorn inbred chicken lines is associated with greater bursal inflammation <i>in vivo</i> and more rapid induction of pro-inflammatory responses in primary bursal cells stimulated <i>ex vivo</i>

2021-03-18

Abstract excerpt

In order to better understand differences in the outcome of infectious bursal disease virus (IBDV) infection, we inoculated a very virulent (vv) strain into White Leghorn chickens of inbred line W that was previously reported to experience over 24% flock mortality, and three inbred lines (15I, C.B4 and 0) that were previously reported to display no mortality. Within each experimental group, some individuals experi...

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Literature Corpus work
64995b73-3574-5461-9731-5bd9fe0827c2
DOI
10.1101/2021.03.18.436042
Open publication

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Transcriptomic analysis reveals that severity of infectious bursal disease in White Leghorn inbred chicken lines is associated with greater bursal inflammation <i>in vivo</i> and more rapid induction of pro-inflammatory responses in primary bursal cells stimulated <i>ex vivo</i>DOI 10.1101/2021.03.18.436042
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