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The stronger downregulation of <i>in vitro</i> and <i>in vivo</i> innate antiviral responses by a very virulent strain of infectious bursal disease virus (IBDV), compared to a classical strain, is mediated, in part, by the VP4 protein

2019-12-18

Abstract excerpt

IBDV is economically important to the poultry industry. Very virulent (vv) strains cause higher mortality rates than other strains for reasons that remain poorly understood. In order to provide more information on IBDV disease outcome, groups of chickens (n=18) were inoculated with the vv strain, UK661, or the classical strain, F52/70. Birds infected with UK661 had a lower survival rate (50%) compared to F52/70 (8...

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Literature Corpus work
6a6cb68b-c667-5a67-9d92-c874588549c7
DOI
10.1101/2019.12.17.879437
Open publication

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The stronger downregulation of <i>in vitro</i> and <i>in vivo</i> innate antiviral responses by a very virulent strain of infectious bursal disease virus (IBDV), compared to a classical strain, is mediated, in part, by the VP4 proteinDOI 10.1101/2019.12.17.879437
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