Article

High-Sensitivity Pan-Cancer AI Assessment of Lymph Node Metastasis via Uncertainty Quantification

2025-12-31

Abstract excerpt

The histological heterogeneity of primary tumours across the pan-cancer spectrum poses a formidable barrier to accurate lymph node metastasis assessment, often causing AI systems to make “overconfident errors” on rare variants that lead to missed diagnoses. To address this, we present UPATHLN, a unified diagnostic platform that synergizes a pathology foundation model-based encoder with a decoupled uncertainty esti...

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Literature Corpus work: 6410b26e-0743-5ad6-a6ca-eb2b3e621940
DOI: 10.64898/2025.12.23.25342895

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