Article

Single-cell transcriptomic analysis reveals impaired mitochondrial gene expression in the podocytes of a child with primary coenzyme Q10 nephropathy.

2024-09-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Coenzyme Q10 (CoQ10) nephropathy is a well-known cause of hereditary steroid-resistant nephrotic syndrome, primarily impacting podocytes. This study aimed to elucidate variations in individual cell-level gene expression in CoQ10 nephropathy using single-cell transcriptomics. <bold>Methods</bold> We conducted single-cell sequencing of a kidney biopsy specimen from...

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Literature Corpus work: 63b1b070-e4a4-52f1-aa8d-729642f1f889
DOI: 10.21203/rs.3.rs-4868504/v1

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Single-cell transcriptomic analysis reveals impaired mitochondrial gene expression in the podocytes of a child with primary coenzyme Q10 nephropathy.DOI 10.21203/rs.3.rs-4868504/v1Read

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