Article
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.
BMC genomics - 4 Nov 2016
Shu Le, Zhao Yuqi, Kurt Zeyneb, Byars Sean Geoffrey, Tukiainen Taru, Kettunen Johannes, Orozco Luz D, Pellegrini Matteo, Lusis Aldons J, Ripatti Samuli, Zhang Bin, Inouye Michael, Mäkinen Ville-Petteri, Yang Xia
Abstract excerpt
BACKGROUND: Complex diseases are characterized by multiple subtle perturbations to biological processes. New omics platforms can detect these perturbations, but translating the diverse molecular and statistical information into testable mechanistic hypotheses is challenging. Therefore, we set out to create a public tool that integrates these data across multiple datasets, platforms, study designs and species in...
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