Article

An HERV-W<i>ENV</i>transcription in atypical memory B cells linked to COVID-19 evolution and risk for long COVID can express the encoded protein from a ribosome readthrough of mRNA from chromosome X

2024-07-03

Abstract excerpt

<h4>ABSTRACT</h4> The human genome comprises 8% of endogenous retroviruses (HERVs). Though HERVS contribute to physiological functions, copies retained pathogenic potential. The HERV-W ENV protein was shown expressed in patients with worse COVID-19 symptoms and post-COVID syndrome. A significant detection of the mRNA encoding HERV-W ENV from patients with COVID-19 in B cells from RNAseq reads obtained from periphe...

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Literature Corpus work: 6313f91f-7737-5953-adc5-45d97fdc2b26
DOI: 10.1101/2024.07.03.24309822

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