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No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial

2019-02-05

Abstract excerpt

<h4>Background: </h4> Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and morbidity. The WOMAN trial showed that tranexamic acid (TXA) reduces death due to bleeding in women with PPH. To determine whether TXA has pro-thrombotic effects in women with PPH, we measured endogenous thrombin potential (ETP), coagulation factors V, VIII, von Willebrand (vW), fibrinogen, D-Dimers and platelet function...

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Literature Corpus work
62c7c7cf-dc83-5c63-9b69-097048b2a84d
DOI
10.12688/wellcomeopenres.14977.1
Open publication

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No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trialDOI 10.12688/wellcomeopenres.14977.1
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