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Malaria and the cell cycle

1 Nov 1996

Abstract excerpt

The current model of cell cycle control features a succession of active cyclin-CDK (cyclin-dependent kinase) complexes, where accumulation of each successive cyclin leads to activation of its associated kinase. Cell fusion experiments have shown that nuclei sharing common cytoplasm progress through the cell cycle in synchrony. During schizogony of Plasmodium falciparum, nuclear division occurs asynchronously, and...

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PMID: 15275278
DOI: 10.1016/0169-4758(96)10068-5

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