Article

The neuronal ceroid lipofuscinosis protein Cln7 regulates neural development from the post-synaptic cell

2018-03-08

Abstract excerpt

The neuronal ceroid lipofuscinoses (NCLs) are a group of fatal, monogenic neurodegenerative disorders with an early onset in infancy or childhood. Despite identification of the genes disrupted in each form of the disease, their normal cellular role and how their deficits lead to disease pathology is not fully understood. Cln7, a major facilitator superfamily domain-containing protein, is affected in a late infanti...

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Literature Corpus work: 624e653f-189d-56db-bedd-2e0e4352911b
DOI: 10.1101/278895

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