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ECLARE: multi-teacher contrastive learning via ensemble distillation for diagonal integration of single-cell multi-omic data

2025-01-27

Abstract excerpt

Integrating multimodal single-cell data such as scRNA-seq and scATAC-seq is key for decoding gene regulatory networks. Still, integration remains challenging due to issues related to feature harmonization and limited quantity of paired data. To address these challenges, we introduce ECLARE , a novel framework combining multi-teacher ensemble knowledge distillation with contrastive learning for integrating unpaire...

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Literature Corpus work
624a7de2-0ea2-5646-8f72-658e712693c4
DOI
10.1101/2025.01.24.634799
Open publication

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ECLARE: multi-teacher contrastive learning via ensemble distillation for diagonal integration of single-cell multi-omic dataDOI 10.1101/2025.01.24.634799
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