Article

Genetic co-occurrence networks identify polymorphisms within ontologies highly associated with preeclampsia

2024-07-10

Abstract excerpt

Polygenic diseases require the co-occurrence of multiple risk variants to initiate a pathology. An example is preeclampsia, a hypertensive disease of pregnancy with no known cure or therapy other than the often-preterm delivery of the neonate and placenta. Preeclampsia is challenging to predict due to symptomatic and outcome heterogeneity. Transcriptomic and genetic analysis suggests that this is a multi-syndromic...

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Literature Corpus work: 617606f3-103b-5e13-a576-d531539b7844
DOI: 10.1101/2024.07.09.24310164

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