Article

Applications of Diquafosol Sodium in Ophthalmology: A Comprehensive Review on Therapeutic Utility

2025-02-06

Abstract excerpt

Diquafosol is a purinergic P2Y2 receptor agonist that is garnering much interest for its potential therapeutic benefits in dry eye disease (DED) management and is used commonly in Asia. Diquafosol’s mechanism of action involves enhancing fluid secretion from conjunctival epithelial cells and promoting mucin secretion, thereby improving tear film stability and ocular surface lubrication. Clinical trials have demons...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6125292e-ccf8-58cc-a5c3-b83530ee730f
DOI: 10.20944/preprints202502.0346.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Applications of Diquafosol Sodium in Ophthalmology: A Comprehensive Review on Therapeutic UtilityDOI 10.20944/preprints202502.0346.v1Read

Management of Dry Eye Disease in Asia: A ReviewSemantic proximity Read

What’s new in dry eye disease diagnosis? Current advances and challengesSemantic proximity Read

Translating Biomarker Discovery: From Bench to Bedside in Dry Eye DiseaseSemantic proximity Read

Recent Trends in Dry Eye Disease Treatment in AsiaSemantic proximity Read

A Network Pharmacology Study on the Qiju Dihuang Pills for Treatment of Dry Eye DiseaseSemantic proximity Read

Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunctionSemantic proximity Read

Reimagining dry eye disease management - a multimodal approach targeting the key pathophysiological drivers.Semantic proximity Read

Unveiling the P2X7 receptor: Exploring its mechanisms, pathogenic role in ocular diseases, and emerging therapeutic potentialSemantic proximity Read

Beyond dry eye: how co-morbidities influence disease phenotype in dry eye disease.Semantic proximity Read

Prevalence and severity of dry eye disease among ophthalmologists and allied ocular care professionalsSemantic proximity Read

Personalised Dry Eye Treatment: The Use of Genetic Testing to Tailor Treatment Plans to Individual PatientsSemantic proximity Read

Modeling dry eye with an air-liquid interface in corneal epithelium-on-a-chipSemantic proximity Read