Article

Elevated expression of FGB predicts poor survival in lung adenocarcinoma patients with tobacco exposure

2019-10-17

Abstract excerpt

<h4>Background: </h4> Tobacco exposure is the most important risk factor for the occurrence and death of lung cancer. Fibrinogen beta chain (FGB), the most abundant coagulation factor in plasma, is putatively involved in tumor progression. This study aimed to evaluate the expression pattern and prognostic value of FGB in lung adenocarcinoma with tobacco exposure. <h4>Methods:</h4> FGB expression in lung adenocarci...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 60727163-a20d-5eb4-90f1-20276269e9d3
DOI: 10.21203/rs.2.16162/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elevated expression of FGB predicts poor survival in lung adenocarcinoma patients with tobacco exposureDOI 10.21203/rs.2.16162/v1Read

Differential expression of lung adenocarcinoma transcriptome with signature of tobacco exposureSemantic proximity Read

Novel risk prediction models for prognosis and immunotherapies of NSCLC based on coagulation and fibrinolysis-related genesSemantic proximity Read

Systematic analysis of expression profiles of HMGB family members for prognostic application in non-small cell lung cancerSemantic proximity Read

Identification and validation of smoking-related genes in lung adenocarcinoma using an in vitro carcinogenesis model and bioinformatics analysisSemantic proximity Read

Role of endothelin receptor type B ( EDNRB) in lung adenocarcinomaSemantic proximity Read

FAM83B promotes the invasion of primary lung adenocarcinoma via PI3K/AKT/NF-κB pathwaySemantic proximity Read

Chromatin Accessibility Reveals Potential Prognostic Value of the Peak Set Associated with Smoking History in Patients with Lung AdenocarcinomaSemantic proximity Read

Effect of active smoking on the human bronchial epithelium transcriptomeSemantic proximity Read

Cumulative smoking dose affects the clinical outcomes of EGFR-mutated lung adenocarcinoma patients treated with EGFR-TKIs: a retrospective study.Semantic proximity Read

Downregulation of m6A reader YTHDC2 promotes the proliferation and migration of lung cancer and cigarette smoke-exposed BEAS-2B cellsSemantic proximity Read

Identification of critical genes and pathways related to venous thromboembolism in non-small cell lung cancer patients using integrated bioinformatics analysisSemantic proximity Read

TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signalingSemantic proximity Read