Article

Somatic DICER1 pathogenic variants in a well-differentiated fetal lung adenocarcinoma diagnosed in a man with familial adenomatous polyposis

2025-07-18

Abstract excerpt

<title>Abstract</title> <p>Well-differentiated fetal lung adenocarcinoma (WDFLAC) is a rare pulmonary carcinoma characterized by its resemblance to the fetal lung. It was thought to be caused by somatic pathogenic variants (PVs) in the genes <italic>CTNNB1</italic> or <italic>APC</italic>, which lead to the nuclear accumulation of beta(β)-catenin and down-stream activation of key oncogenes. However, recent studie...

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Literature Corpus work: 606c6160-d7a3-5f7f-8fea-0b0a9d5819d8
DOI: 10.21203/rs.3.rs-7013135/v1

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