Article
DICER1 syndrome can mimic different genetic tumor predispositions.
Cancer letters - 28 Jan 2016
Mehraein Yasmin, Schmid Irene, Eggert Marlene, Kohlhase Jürgen, Steinlein Ortrud K
Abstract excerpt
DICER1, a RNAse endonuclease involved in the processing of siRNA and microRNA, is known to play a pivotal role in the post-transcriptional regulation of gene expression. Germ line mutations in the DICER1 gene increase the risk for different types of tumors. At present, DICER1 syndrome is an established, though not well defined, member of the group of genetic tumor predisposition syndromes. Here, we report a...
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