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Article

Silencing of MEG3 attenuated the role of lipopolysaccharides by modulating the miR-93-5p/PTEN pathway in Leydig cells

2020-09-22

Abstract excerpt

<h4>Background: </h4> Leydig cells reflect the activation of inflammation, decrease of androgen production, inhibition of cell growth and promotion of cell apoptosis under orchitis. Maternally expressed gene 3 (MEG3) exerts a crucial role in various human diseases, but under orchitis, the role and underlying molecular mechanism of MEG3 in Leydig cells remain unclear.MethodsLipofectamine 2000 was used for the cell...

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Literature Corpus work
5ff2658b-eb5b-555e-b875-1387e1942b04
DOI
10.21203/rs.3.rs-73472/v1
Open publication

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Silencing of MEG3 attenuated the role of lipopolysaccharides by modulating the miR-93-5p/PTEN pathway in Leydig cellsDOI 10.21203/rs.3.rs-73472/v1
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