Article
Developments in therapeutics for pulmonary arterial hypertension.
Minerva cardioangiologica - 1 Jun 2002
Wilkins M R, Møller G M O, Ren X, Wharton J
Abstract excerpt
For many years, the management of pulmonary hypertension has been frustrated by an inadequate understanding of its pathology and limited therapeutic options, but this is changing rapidly. Recently, novel insight into the pathogenesis of primary pulmonary hypertension (PPH) has been provided by the demonstration of mutations in BMPR2 and ALK-1 genes in a significant number of patients with the condition. These...
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