Article

Developing a phosphodiesterase-5 inhibitor assay to detect counterfeit drugs containing phosphodiesterase-5 inhibitors using spectrophotometry

2019-09-26

Abstract excerpt

<h4>Background: </h4> Phosphodiesterase-5 inhibitors (PDE5i) are the first line of drugs used for the treatment of erectile dysfunction. PDE5i inhibits the activities of phosphodiesterase-5 (PDE5) found in corpus cavernosum reducing production of guanosine monophosphate (GMP) that results in vasodilation of blood vessels thereby prolonging penile erection. Various counterfeit drugs adulterated with unknown levels...

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Literature Corpus work: 5e3530e5-2550-5bc7-a884-56653a0ad0ce
DOI: 10.12688/f1000research.19500.1

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