Semaglutide Reverses the Chronic Myopathy of Hyperkalemic Periodic Paralysis: A Case Report

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Hyperkalemic Periodic Paralysis (HPP) is an autosomal dominant genetic disorder where high extracellular potassium depolarizes skeletal muscle and triggers painful sustained contractions that lead to permanent myopathy. Interventions have typically relied on acetazolamide and diclofenamide with limited success. <bold>Case Presentation: </bold>The patient is a 48...

Topics

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• Channelopathies
• Genetic Predisposition to Disease
• Ion Channel Gating
• Ion Channels
• Muscle Contraction
• Muscle, Skeletal
• Mutation
• Paralyses, Familial Periodic

Identifiers and source

Literature Corpus work

5e2464ad-54ec-5940-b637-21e7c6524108

DOI

10.21203/rs.3.rs-4908191/v1