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A novel enhancer RNA, Hmrhl, positively regulates its host gene, <i>phkb,</i> in Chronic Myelogenous Leukemia

2018-07-27

Abstract excerpt

Noncoding RNAs are increasingly being accredited with key roles in gene regulation during development and disease. Here we report the discovery and characterization of a novel long noncoding RNA, Hmrhl, which shares synteny and partial sequence similarity with the mouse lncRNA, Mrhl. The human homolog, Hmrhl, transcribed from intron 14 of phkb gene, is 5.5kb in size, expressed in all tissues examined and has acqu...

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Literature Corpus work
5df69020-1011-57a8-a22f-5c6269412046
DOI
10.1101/378984
Open publication

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