Article
Sulforaphane Modulates Joint Inflammation in a Murine Model of Complete Freund's Adjuvant-Induced Mono-Arthritis.
Molecules (Basel, Switzerland) - 24 Apr 2018
Silva Rodrigues João Francisco, Silva E Silva Cristiane, França Muniz Thayanne, de Aquino Alana Fernanda, Neuza da Silva Nina Larissa, Fialho Sousa Nagila Caroline, Nascimento da Silva Luis Claudio, de Souza Breno Glaessner Gomes Fernandes, da Penha Tatiana Aranha, Abreu-Silva Ana Lúcia, de Sá Joicy Cortez, Soares Fernandes Elizabeth, Grisotto Marcos Augusto Grigolin
Abstract excerpt
Rheumatoid arthritis (RA) is characterized by inflammation of one or more joints, and affects ~1% of the adult population worldwide. Sulforaphane (SFN) is a natural compound that has been suggested as an antioxidant. Here, SFN’s effects were evaluated in a murine mono-arthritis model. Mono-arthritis was induced in mice by a single intra-articular injection of Complete Freund’s Adjuvant (CFA-10 µg/joint, in 10 µL)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.