Focused ultrasound-mediated drug delivery of bevacizumab in treating NF2-related schwannomatosis in an animal model

Abstract excerpt

<title>Abstract</title> <p>Neurofibromatosis type 2 (NF2)-related schwannomatosis is an autosomal dominant genetic disorder characterized by the development of cranial and peripheral nerve schwannomas, including bilateral vestibular schwannomas and dorsal root ganglion schwannomas along the spinal axis, both of which are associated with substantial morbidity. Current therapeutic strategies comprise surgical resec...

Topics

Open a Topic to create a Post that cites this publication.

• Child
• Genetic Predisposition to Disease
• Mitogen-Activated Protein Kinase Kinases
• Neurofibromatoses
• Neurofibromatosis 1
• Neurofibromatosis and Schwannoma Cases
• Protein Kinase Inhibitors
• Vascular Endothelial Growth Factor A

Identifiers and source

Literature Corpus work

5d649e86-01ce-5bdb-987d-99aaabc5aed2

DOI

10.21203/rs.3.rs-7273065/v1