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Outburst of serotype 4 IPD after COVID-19 is driven by ST15063/GPSC162 lineage associated with high-risk behaviors and greater virulence linked to influenza H3N2 virus coinfection and cigarette smoke

2026-03-04

Abstract excerpt

<h4>ABSTRACT</h4> The emergence of vaccine covered serotypes causing invasive pneumococcal disease (IPD) is a serious concern worldwide. We investigated the unexpected rise of serotype 4 causing IPD primarily in non-vaccinated young adults after the COVID-19 pandemic that further spread to adults ≥ 65 years in recent years. For this purpose, we conducted a retrospective study of serotype 4 IPD cases (n=827) repor...

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Literature Corpus work
5cf9ecc1-efc0-5765-af08-70a229171c24
DOI
10.64898/2026.02.27.26346872
Open publication

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Outburst of serotype 4 IPD after COVID-19 is driven by ST15063/GPSC162 lineage associated with high-risk behaviors and greater virulence linked to influenza H3N2 virus coinfection and cigarette smokeDOI 10.64898/2026.02.27.26346872
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