Article

Dendro-plexing single input spikes by multiple synaptic contacts enriches the computational capabilities of cortical neurons and reduces axonal wiring

2022-01-28

Abstract excerpt

A cortical neuron typically makes multiple synaptic contacts on the dendrites of its postsynaptic target neuron. The functional implications of this apparent redundancy are unclear. Due to dendritic cable filtering, proximal dendritic synapses generate brief somatic postsynaptic potentials (PSPs) whereas distal synapses give rise to broader PSPs. Consequently, with multiple synaptic contacts, a single presynaptic...

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Literature Corpus work: 5cd4a1a5-05d7-59c1-a6e9-356b8cc2b5c9
DOI: 10.1101/2022.01.28.478132

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