Article
Lethal toxicity of anticancer drugs in Xeroderma pigmentosum
2022-12-27
Abstract excerpt
Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by defective DNA repair, leading to hypersensitivity to ultraviolet (UV) sunlight and predisposes to various cutaneous and non-cutaneous malignancies. Platinum compounds are used against cutaneous cancers as concurrent chemoradiotherapy. But the XP gene polymorphism has a potential role in metabolism of these agents and their susceptibility. Here, w...
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Identifiers and source
- Literature Corpus work
- 5ace632e-dacd-561c-ba5a-178bf0459142
- DOI
- 10.22541/au.167213142.27112737/v1
