Xeroderma Pigmentosum: General Aspects and Management

Abstract excerpt

Xeroderma Pigmentosum (XP) is a rare genetic syndrome with a defective DNA nucleotide excision repair. It is characterized by (i) an extreme sensitivity to ultraviolet (UV)-induced damages in the skin and eyes; (ii) high risk to develop multiple skin tumours; and (iii) neurologic alterations in the most severe form. To date, the management of XP patients consists of (i) early diagnosis; (ii) a long-life...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinogens and Genotoxicity Assessment
• Share to DNA Repair Mechanisms
• Share to Skin Protection and Aging