Article

Bridging and analytical validation of the Prosigna <sup>®</sup> Breast Risk of Recurrence Test as a whole-transcriptome NGS lab developed test

2026-06-25

Abstract excerpt

<h4>Background</h4> The Prosigna Breast Risk of Recurrence test is based on the PAM50 classifier and was originally validated as an in vitro diagnostic (IVD) test on the Dx enabled nCounter ® Analysis System. The Prosigna test is intended for early-stage, hormone receptor+ (HR+) breast cancer and provides the risk of recurrence (ROR) score (0-100), intrinsic subtype (Luminal A, Luminal B, HER2-enriched, and Bas...

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Literature Corpus work: 5a541da9-5ec3-58dc-903a-782c6a4c3b36
DOI: 10.64898/2026.06.23.26355479

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