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Mucosal innate immune activation as the trigger to <i>Prevotella</i> species-induced arthritis in genetically resistant mice

2025-03-19

Abstract excerpt

An altered gut microbiota, particularly the expansion of Prevotellaceae members, is increasingly implicated in the pathogenesis of rheumatoid arthritis (RA), yet the mechanisms hind this phenomenon remain unclear. Here, we demonstrate that Palleniella intestinalis , a member of the Prevotellaceae family, induces a 100% arthritis incidence in genetically resistant C57BL/6 mice. Inoculation with P. intestinalis...

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Identifiers and source

Literature Corpus work
5a4e75b6-5889-5753-aa97-2918d1276d26
DOI
10.1101/2025.03.18.643707
Open publication

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Mucosal innate immune activation as the trigger to <i>Prevotella</i> species-induced arthritis in genetically resistant miceDOI 10.1101/2025.03.18.643707
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