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Article

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

5 Nov 2013

Abstract excerpt

Rheumatoid arthritis (RA) is a prevalent systemic autoimmune disease, caused by a combination of genetic and environmental factors. Animal models suggest a role for intestinal bacteria in supporting the systemic immune response required for joint inflammation. Here we performed 16S sequencing on 114 stool samples from rheumatoid arthritis patients and controls, and shotgun sequencing on a subset of 44 such...

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PMID: 24192039
DOI: 10.7554/elife.01202

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