Therapeutic monitoring of the host-bacterium-phage interaction in a child

Abstract excerpt

<title>Abstract</title> <p>Successful phage therapy for extensive chronic osteoarticular infection in a child resulted in an initial flush of bacterial contents into the bloodstream with an inflammatory response marked by fever, local pain and upregulation of genes associated with autophagy and innate immunity. Monitoring of phage and bacterial kinetics and the human host response allowed early dose adjustment an...

Topics

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• Advanced biosensing and bioanalysis techniques
• Aquaculture disease management and microbiota
• Bacillus and Francisella bacterial research
• Bacteriophages and microbial interactions
• Microbial infections and disease research
• Monoclonal and Polyclonal Antibodies Research
• Orthopedic Infections and Treatments
• Plant Virus Research Studies

Identifiers and source

Literature Corpus work

59f5fc27-b943-58c6-a071-8067857f0d6f

DOI

10.21203/rs.3.rs-110673/v1