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Article

Unsupervised co-optimization of a graph neural network and a knowledge graph embedding model to prioritize causal genes for Alzheimer’s Disease

2022-10-06

Abstract excerpt

1. Data obtained from clinical trials for a given disease often capture reliable empirical features of the highest quality which are limited to few studies/experiments. In contrast, knowledge data extracted from biomedical literature captures a wide range of clinical information relevant to a given disease that may not be as reliable as the experimental data. Therefore, we propose a novel method of training that c...

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Literature Corpus work
596d8335-2605-5349-aa6d-1bc0b2c8ad7f
DOI
10.1101/2022.10.03.22280657
Open publication

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Unsupervised co-optimization of a graph neural network and a knowledge graph embedding model to prioritize causal genes for Alzheimer’s DiseaseDOI 10.1101/2022.10.03.22280657
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