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Calcitonin Gene-related Peptide mRNA Synthesis in Trigeminal Ganglion Neurons after Cortical Spreading Depolarization

2023-05-03

Abstract excerpt

Migraine is a debilitating neurovascular disorder characterized by recurrent headache attacks of moderate to severe intensity. Calcitonin gene-related peptide (GGRP), which is abundantly expressed in trigeminal ganglion (TG) neurons, plays a crucial role in migraine pathogenesis. Cortical spreading depolarization (CSD), the biological correlate of migraine aura, activates the trigeminovascular system. In the prese...

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Literature Corpus work
59435faf-47b4-5861-af9a-debfc6a7240e
DOI
10.20944/preprints202305.0088.v1
Open publication

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Calcitonin Gene-related Peptide mRNA Synthesis in Trigeminal Ganglion Neurons after Cortical Spreading DepolarizationDOI 10.20944/preprints202305.0088.v1
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