Article

Neurofibromatosis Type I (NF1) and Bone Involvement in a pediatric setting: Insights from FGF23 Levels

2024-10-24

Abstract excerpt

<title>Abstract</title> <p>Background Neurofibromatosis type I (NF1) is an autosomal dominant disorder characterized by extremely different phenotypes, sometimes including reduced bone mass. The underlying cause of bone impairment in these patients remains poorly understood, especially in children. Previous studies in mice and single reports in NF1 patients with osteomalacia have shown elevated serum FGF23 level...

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Literature Corpus work: 591ec926-ba65-5c8c-820a-ff546c9c0d59
DOI: 10.21203/rs.3.rs-4957214/v1

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