Article

The edible tomato COVID-19 vaccine, TOMAVAC, induces neutralising IgGs

2023-01-06

Abstract excerpt

<title>Abstract</title> <p>Plant-based edible vaccines that provide two-layered protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outweigh the currently used parenteral type of vaccines, predominantly causing a systemic immune response. Here we engineered and selected the transgenic tomato genotype (TOMOVAC), stably synthesising an antigenic S1 protein of SARS-COV-2. Two-course space...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 58e3f0da-39b9-53a7-bc3b-1cb973531108
DOI: 10.21203/rs.3.rs-2447951/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The edible tomato COVID-19 vaccine, TOMAVAC, induces neutralising IgGsDOI 10.21203/rs.3.rs-2447951/v1Read

High efficacy of VLA2001 vaccine against SARS-CoV-2 infection in non-human primatesSemantic proximity Read

Immunogenicity of adjuvanted plant-produced SARS-CoV-2 Beta spike VLP vaccine in New Zealand white rabbitsSemantic proximity Read

Cold-Adapted Live Attenuated SARS-Cov-2 Vaccine Completely Protects Human ACE2 Transgenic Mice from SARS-Cov-2 InfectionSemantic proximity Read

Efficacy and Safety of a Plant-Based Virus-Like Particle Vaccine for COVID-19 Adjuvanted with AS03Semantic proximity Read

Cornering an Ever-Evolving Coronavirus: TATX-03, a fully human synergistic multi-antibody cocktail targeting the SARS-CoV-2 Spike Protein with <i>in vivo</i> efficacySemantic proximity Read

CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2Semantic proximity Read

Plant-produced RBD and cocktail-based vaccine candidates are highly effective against SARS-CoV-2, independently of its emerging variantsSemantic proximity Read

Covering All Bases: A Computational Method to Design Broad-spectrum T-cell-inducing Vaccines Applied to <i>Betacoronaviruses</i>Semantic proximity Read

SARS-CoV-2 oral tablet vaccination induces neutralizing mucosal IgA in a phase 1 open label trialSemantic proximity Read

SpiN-Tec: A T cell-based recombinant vaccine that is safe, immunogenic, and shows high efficacy in experimental models challenged with SARS-CoV-2 variants of concernSemantic proximity Read

Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19 disease in hamstersSemantic proximity Read

Transient production of Receptor-Binding Domain of SARS-CoV-2 in Nicotiana benthamiana plants induces specific antibodies in immunized miceSemantic proximity Read