Article

Susceptibility haplotypes in non-cystic fibrosis newborns with elevated immunoreactive trypsinogen

2026-08-05

Abstract excerpt

Cystic fibrosis (CF) represents the most prevalent life-threatening autosomal recessive disorder in Europe, primarily affecting the respiratory tract, exocrine pancreatic function, and lipid metabolism. Immunoreactive trypsinogen (IRT) quantification constitutes the first-tier test in neonatal CF screening programs; however, elevated IRT levels may also be detected in infants who do not develop CF, generating fals...

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Literature Corpus work: 58c11de4-71b3-50e5-96cb-e9cac8e4f994
DOI: 10.1186/s10020-026-01581-7

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