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Article

Cystic fibrosis carriers have higher neonatal immunoreactive trypsinogen values than non-carriers.

American journal of medical genetics. Part A - 1 Jun 2005

Castellani Carlo, Picci Luigi, Scarpa Maurizio, Dechecchi Maria Cristina, Zanolla Luisa, Assael Baroukh Maurice, Zacchello Franco

Abstract excerpt

Following cystic fibrosis (CF) neonatal screening implementation, a high frequency of heterozygotes has been reported among neonates with elevated immunoreactive trypsinogen (IRT) and normal sweat chloride levels. We studied the relationship between normal IRT values and CF heterozygosity: 10,000 neonates were screened for CF by IRT measurement and tested for 40 CF mutations; the 294 carriers detected were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 15832355
DOI: 10.1002/ajmg.a.30470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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