The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia

Abstract excerpt

Preeclampsia (PE) is a serious complication of pregnancy with a pathogenesis that is not fully understood, though it involves the impaired invasion of extravillous trophoblasts (EVTs) into the decidual layer during implantation. Recently, others have found that diverse cell types, including EVTs, produce exosomes filled with molecular cargo (mainly proteins and RNAs) that can be transported to other cells and orga...

Topics

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• Birth, Development, and Health
• Cancer-related molecular mechanisms research
• Extracellular vesicles in disease
• Gestational Diabetes Research and Management
• MicroRNA in disease regulation
• Pregnancy and preeclampsia studies
• Preterm Birth and Chorioamnionitis
• Reproductive System and Pregnancy

Identifiers and source

Literature Corpus work

5867a52f-d5b3-5aea-bf0f-85f5dc2d1570

DOI

10.20944/preprints202305.1713.v1