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Human Placenta Exosomes: Biogenesis, Isolation, Composition, and Prospects for Use in Diagnostics

22 Feb 2021

Abstract excerpt

Exosomes are 40-100 nm nanovesicles participating in intercellular communication and transferring various bioactive proteins, mRNAs, miRNAs, and lipids. During pregnancy, the placenta releases exosomes into the maternal circulation. Placental exosomes are detected in the maternal blood even in the first trimester of pregnancy and their numbers increase significantly by the end of pregnancy. Exosomes are necessary...

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PMID: 33671527
DOI: 10.3390/ijms22042158

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