Article

Cardiovascular Signatures of COVID-19 Predict Mortality and Identify Barrier Stabilizing Therapies

2022-02-09

Abstract excerpt

<h4>STRUCTURED ABSTRACT</h4> <h4>Background</h4> Endothelial cell (EC) activation, endotheliitis, vascular permeability, and thrombosis have been observed in patients with severe COVID-19, indicating that the vasculature is affected during the acute stages of SARS-CoV-2 infection. It remains unknown whether circulating vascular markers are sufficient to predict clinical outcomes, are unique to COVID-19, and if vas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 583bf875-db68-5608-8d64-39cb522a6b98
DOI: 10.1101/2022.02.08.22270636

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cardiovascular Signatures of COVID-19 Predict Mortality and Identify Barrier Stabilizing TherapiesDOI 10.1101/2022.02.08.22270636Read

Vascular underpinning of COVID-19Semantic proximity Read

Plasma Proteome of Long-covid Patients Indicates Hypoxia-mediated Vasculo-proliferative Disease With Impact on Brain and Heart FunctionSemantic proximity Read

Transcriptomic profiling of disease severity in patients with COVID-19 reveals role of blood clotting and vasculature related genesSemantic proximity Read

Protein C Pretreatment Protects Endothelial Cells from SARS-CoV-2-Induced ActivationSemantic proximity Read

Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19Semantic proximity Read

<strong></strong>An In-Depth Insight into Clinical, Cellular and Molecular Factors in COVID19-Associated Cardiovascular Ailments for Identifying Novel Disease Biomarkers, Drug Targets and Clinical Management StrategiesSemantic proximity Read

Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19Semantic proximity Read

Endothelial activation and dysfunction in COVID-19: from basic mechanisms to potential therapeutic approachesSemantic proximity Read

An In-Depth Insight into Clinical, Cellular and Molecular Factors in COVID-19-Associated Cardiovascular Ailments for Identifying Novel Disease Biomarkers, Drug Targets and Clinical Management StrategiesSemantic proximity Read

Endothelial Cell Contributions to COVID-19Semantic proximity Read

Dynamic gene expression analysis reveals distinct severity phases of immune and cellular dysregulation in COVID-19Semantic proximity Read

Genetic and Epigenetic Intersections in COVID-19-Associated Cardiovascular Disease: Emerging Insights and Future DirectionsSemantic proximity Read