Article

Mesothelioma Interactome with 367 Novel Protein-Protein Interactions

2018-11-01

Abstract excerpt

Malignant pleural mesothelioma (MPM) is an aggressive cancer of the thorax with a median survival of one year. We constructed an ‘MPM interactome’ with over 300 computationally predicted PPIs and over 1300 known PPIs of 62 literature-curated genes whose activity affects MPM. Known PPIs of the 62 MPM associated genes were derived from BioGRID and HPRD databases. Novel PPIs were predicted by applying the HiPPIP algo...

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Literature Corpus work: 58099c88-bd22-5ec7-9e8d-986cef1f6aae
DOI: 10.1101/459065

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