Back to search

Article

Quorum sensing and capsule expression enable subpopulation evasion of phage killing in <i>Escherichia coli</i> ST131: Implications for targeted therapy

2026-04-08

Abstract excerpt

Escherichia coli ST131 is a globally disseminated multidrug-resistant lineage frequently associated with recalcitrant urinary tract infections (UTIs) and bacteraemia. While bacteriophages offer a promising alternative treatment to antibiotics, their efficacy is often limited in physiologically relevant conditions in comparison to laboratory media. In this study, we have investigated the mechanisms by which the rep...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
57fb742b-ec01-51bb-8a95-0b620e2de9a0
DOI
10.64898/2026.04.07.717128
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Quorum sensing and capsule expression enable subpopulation evasion of phage killing in <i>Escherichia coli</i> ST131: Implications for targeted therapyDOI 10.64898/2026.04.07.717128
Phage resistance accompanies reduced fitness of uropathogenic <i>E. coli</i> in the urinary environmentSemantic proximity
The rise, fall, and resurgence of phage therapy for urinary tract infectionSemantic proximity
Harnessing Lytic Phages for Biofilm Control in Carbapenem-Resistant <i>Klebsiella pneumoniae</i> Causing Urinary Tract InfectionSemantic proximity
Variable effects on virulence of bacteriophage resistance mechanisms in extraintestinal pathogenic <i>Escherichia coli</i>Semantic proximity
Acquired CRISPR spacers and rhamnose-glucose polysaccharide defects confer resistance to <i>Streptococcus mutans</i> phage ɸAPCM01Semantic proximity
Bacteriophage-mediated reduction of uropathogenic <i>E. coli</i> from the urogenital epitheliumSemantic proximity
Phenotypic Heterogeneity Shapes Phage Resistance and Cocktail Efficacy in <i>Klebsiella pneumoniae</i>Semantic proximity
Lytic bacteriophages active in urine against multi-drug resistant clinically derived <i>Klebsiella pneumoniae</i> causing urinary tract infectionSemantic proximity
Joint antibiotic and phage therapy: addressing the limitations of a seemingly ideal phage for treating <i>Staphylococcus aureus</i> infectionsSemantic proximity
Mucin modulates phage infection dynamics and biofilm formation in enteropathogenic <i>Yersinia enterocolitica</i>Semantic proximity
Characterization and therapeutic potential of phage vB_Eco_ZCEC08 against multidrug-resistant uropathogenic Escherichia coliSemantic proximity
High-throughput mapping of the phage resistance landscape in <i>E. coli</i>Semantic proximity
Select a neighboring publication to make it the new centre.