Article

Biofilms and core pathogens shape the tumour microenvironment and immune phenotype in colorectal cancer

2023-10-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Growing evidence links bacterial dysbiosis with colorectal cancer (CRC) carcinogenesis, characterized by an increased presence of core pathogens such as Bacteroides fragilis and Fusobacterium nucleatum . Here, we characterized the in situ biogeography and transcriptional interactions between bacteria and the host in mucosal colon biopsies. <h4>Design</h4> The influence o...

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Literature Corpus work: 57e8fb4b-f817-5962-842f-b45ef3e9e0ef
DOI: 10.1101/2023.10.20.563034

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