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Article

Biofilms and core pathogens shape the tumor microenvironment and immune phenotype in colorectal cancer.

Gut microbes - 1 Jan 2000

Kvich Lasse, Fritz Blaine Gabriel, Zschach Henrike, Terkelsen Thilde, Raskov Hans, Høst-Rasmussen Kathrine, Jakobsen Morten Ragn, Gheorghe Alexandra Gabriella, Gögenur Ismail, Bjarnsholt Thomas

Abstract excerpt

Extensive research has explored the role of gut microbiota in colorectal cancer (CRC). Nonetheless, metatranscriptomic studies investigating the in situ functional implications of host-microbe interactions in CRC are scarce. Therefore, we characterized the influence of CRC core pathogens and biofilms on the tumor microenvironment (TME) in 40 CRC, paired normal, and healthy tissue biopsies using fluorescence in...

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Identifiers

PMID: 38726597
DOI: 10.1080/19490976.2024.2350156
PMCID: PMC11093030

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