Article

Optimal control of a delayed hepatitis B viral infection model with HBV DNA‐containing capsids and CTL immune response

2018-01-12

Abstract excerpt

Summary This paper deals with an optimal control problem of a time‐delayed differential equation model that describes the interactions between hepatitis B virus (HBV) with HBV DNA‐containing capsids, liver cells (hepatocytes), and cytotoxic T‐lymphocyte immune response. Both the treatment and the intracellular delay are incorporated into the model. Furthermore, the existence of the optimal control pair is studied,...

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Literature Corpus work: 57ad628f-d14c-5d2d-9b71-c890fe9c9cf0
DOI: 10.1002/oca.2407

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