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Article

Global stability of an HIV-1 model with distributed intracellular delays and a combination therapy

1 Jan 2010

Abstract excerpt

Global stability is analyzed for a general mathematical model of HIV-1 pathogenesis proposed by Nelson and Perelson [11]. The general model include two distributed intracellular delays and a combination therapy with a reverse transcriptase inhibitor and a protease inhibitor. It is shown that the model exhibits a threshold dynamics: if the basic reproduction number is less than or equal to one, then the HIV-1...

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PMID: 20578792
DOI: 10.3934/mbe.2010.7.675

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