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Mesenchymal Stromal Cells in the Bone Marrow Niche Consist of Multi-Populations With Distinct Transcriptional and Epigenetic Properties

2021-01-13

Abstract excerpt

Although multiple studies have investigated the mesenchymal stem and progenitor cells (MSCs) that give rise to mature bone marrow, high heterogeneity in their morphologies and properties causes difficulties in molecular separation of their distinct populations. In this study, by taking advantage of the resolution of the single cell transcriptome, we analyzed Sca-1 and PDGFR-α fraction in the mouse bone marrow tiss...

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Literature Corpus work
5786e01b-0a3f-5989-b6b8-091211bb6b50
DOI
10.21203/rs.3.rs-138736/v1
Open publication

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Mesenchymal Stromal Cells in the Bone Marrow Niche Consist of Multi-Populations With Distinct Transcriptional and Epigenetic PropertiesDOI 10.21203/rs.3.rs-138736/v1
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