Article

Dynamics of organelle DNA segregation in <i>Arabidopsis</i> development and reproduction revealed with tissue-specific heteroplasmy profiling and stochastic modelling

2022-11-08

Abstract excerpt

Organelle DNA (oDNA) in mitochondria and plastids is vital for plant (and eukaryotic) life. Selection against damaged oDNA is mediated in part by segregation – the sorting of different oDNA types into different cells in the germline. Plants segregate oDNA very rapidly, with oDNA recombination protein MutS Homolog 1 (MSH1), a key driver of this segregation, but in contrast to mammals, we have very limited knowledge...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 570b548c-f138-59c5-a832-1e35ff14e60b
DOI: 10.1101/2022.11.07.515340

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamics of organelle DNA segregation in <i>Arabidopsis</i> development and reproduction revealed with tissue-specific heteroplasmy profiling and stochastic modellingDOI 10.1101/2022.11.07.515340Read

Sorting of mitochondrial and plastid heteroplasmy in Arabidopsis is extremely rapid and depends on MSH1 activitySemantic proximity Read

Optimal Organelle Inheritance Strategies Under Different Changing Environments and Mutational Pressures.Semantic proximity Read

MSH1 is required for maintenance of the low mutation rates in plant mitochondrial and plastid genomes.Semantic proximity Read

Testing Weismann's germ plasm theory in Arabidopsis.Semantic proximity Read

Plant Mitochondrial Genomes: Dynamics and Mechanisms of Mutation.Semantic proximity Read

Double-strand break repair processes drive evolution of the mitochondrial genome in Arabidopsis.Semantic proximity Read

Disruption of recombination machinery alters the mutational landscape in plant organellar genomes.Semantic proximity Read

Selection for mitochondrial quality drives evolution of the germlineSemantic proximity Read

Dynamics of male meiotic recombination frequency during plant development using Fluorescent Tagged Lines in Arabidopsis thaliana.Semantic proximity Read

Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck.Semantic proximity Read

The mutational hazard hypothesis of organelle genome evolution: 10 years on.Semantic proximity Read

Mitotic gene conversion can be as important as meiotic conversion in driving genetic variability in plants and other species without early germline segregation.Semantic proximity Read